Using stands like the DS1s and DS2s will angle the speakers upwards, which can be a positive thing depending as well as other variables in your setup.  The closer the speakers tweeters are aimed to your ears, the more you will perceive higher frequencies, which are very directional, and using these stands can achieve this.  Some customers prefer having the tweeters off axis a bit, as this results in a less pronounced high end moving the focal point lower.  

There are a ton of options and it really comes down to personal preference, so we highly recommend trying a few different placements / toe-in / toe-out etc. to see what seems to work out best in your setup.